Refractory nephrotic syndrome in focal and segmental glomerulosclerosis by pmm2 genetic variant

Introduction: Nephrotic syndrome (NS) is a clinical condition charac terized by massive proteinuria, edema, hypoalbuminemia, and hyper lipidemia. The etiology may be secondary to systemic, metabolic, infectious, neoplastic, and pharmacological diseases. There is a group of primary causes of unknown...