Naphthyl-functionalized acetamide derivatives: Promising agents for cholinesterase inhibition and antioxidant therapy in Alzheimer's disease
This study presents the synthesis and characterization of a series of 13 novel acetamides. These were subjected to Ellman's assay to determine the efficacy of the AChE and BChE inhibitors. Finally, we report their antioxidant activity as an alternative approach for the search for drugs to treat...
- Autores:
-
Camargo-Ayala, Lorena
Prent-Peñaloza, Luis
Osorio, Edison
Camargo-Ayala, Paola Andrea
Jimenez, Claudio A
Zúñiga-Arbalti, Felipe
Brito, Iván
Delgado, Gerzon E
Gutiérrez John Alexander
Polo-Cuadrado, Efraín
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2024
- Institución:
- Universidad de Ibagué
- Repositorio:
- Repositorio Universidad de Ibagué
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unibague.edu.co:20.500.12313/5534
- Acceso en línea:
- https://hdl.handle.net/20.500.12313/5534
https://www.sciencedirect.com/science/article/pii/S0045206824008010
- Palabra clave:
- Alzheimer
Acetamida - Funcionalidades
Alzheimer - Terapia antioxidante
Acetamide compound
Alzheimer's disease
Antioxidant activity
Cholinesterase inhibitor
Crystallography
- Rights
- closedAccess
- License
- © 2024 Elsevier Inc.