Association of GWAS Top Genes With Late-Onset Alzheimer’s Disease in Colombian Population

ABSTRACT: Objective: The association of variants in CLU, CR1, PICALM, BIN1, ABCA7, and CD33 genes with late-onset Alzheimer’s disease (LOAD) was evaluated and confirmed through genome-wide association study. However, it is unknown whether these associations can be replicated in admixed populations....

Full description

Autores:

Moreno García, Diana Jennifer
Ruíz Mendoza, Susana
Ríos Gallardo, Angela Magnolia
Lopera Restrepo, Francisco Javier
Ostos Alfonso, Henry
Marc Via, Marc
Bedoya Berrío, Gabriel de Jesús

Tipo de recurso:

Article of investigation

Fecha de publicación:

2017

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

spa

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/26742

Acceso en línea:

http://hdl.handle.net/10495/26742

Palabra clave:

Polymorphism Genetic
Polimorfismo Genético
Enfermedad de Alzheimer
Alzheimer Disease
Genética
Genetics

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/