Human macrophages differentiated in the presence of vitamin D3 restrict dengue virus infection and innate responses by downregulating mannose receptor expression
ABSTARCT: Severe dengue disease is associated with high viral loads and overproduction of pro-inflammatory cytokines, suggesting impairment in the control of dengue virus (DENV) and the mechanisms that regulate cytokine production. Vitamin D3 has been described as an important modulator of immune re...
- Autores:
-
Arboleda Alzate, John
Urcuqui Inchima, Silvio
Hernández López, Juan Carlos
Rodenhuis Zybert, Izabela A.
Smit, Jolanda M
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2017
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/11999
- Acceso en línea:
- http://hdl.handle.net/10495/11999
- Palabra clave:
- Cholecalciferol
Dengue
macrophages
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by/4.0/