Tuberculin Skin Test Reactivity is Dependent on Host Genetic Background in Colombian Tuberculosis Household Contacts

ABSTRACT: The tuberculin skin test (TST) measures the intensity of antimycobacterial acquired immunity and is used to diagnose latent infection with Mycobacterium tuberculosis. We report evidence for a codominant gene explaining 65% of the TST variability. Disregarding the host genetic background ma...

Full description

Autores:

Arbeláez Montoya, María Patricia
Barrera Robledo, Luis Fernando
Henao Vanegas, Hanna Marisol
García Moreno, Luis Fernando
Cobat, Aurélie
Abel, Laurent
Schurr, Erwin
Alcaïs, Alexandre

Tipo de recurso:

Article of investigation

Fecha de publicación:

2012

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/36478

Acceso en línea:

https://hdl.handle.net/10495/36478

Palabra clave:

Prueba de Tuberculina
Tuberculin Test
Pruebas Cutáneas
Skin Tests
Inmunidad Adaptativa
Mycobacterium tuberculosis
Antecedentes Genéticos
Genetic Background
Diagnóstico
Diagnosis
Variación Genética
Genetic Variation
Tuberculosis Latente - diagnóstico
Latent Tuberculosis - diagnosis
Tuberculosis Latente - genética
Latent Tuberculosis - genetics
Tuberculosis Latente - inmunología
Latent Tuberculosis - immunology

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/