Dual RNA Sequencing of Mycobacterium tuberculosis-Infected Human Splenic Macrophages Reveals a Strain-Dependent Host-Pathogen Response to Infection

ABSTRACT: Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb), leading to pulmonary and extrapulmonary TB, whereby Mtb is disseminated to many other organs and tissues. Dissemination occurs early during the disease, and bacteria can be found first in the lymph nodes adjacent to the lungs...

Full description

Autores:

Barrera Robledo, Luis Fernando
Alzate Restrepo, Juan Fernando
López Agudelo, Víctor Alonso
Cabarcas Jaramillo, Felipe
Barrera Enríquez, Vianey Paola
Ríos Estepa, Rigoberto
Baena García, Andrés

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39546

Acceso en línea:

https://hdl.handle.net/10495/39546

Palabra clave:

Interacciones Huésped-Patógeno
Host-Pathogen Interactions
Mycobacterium tuberculosis
Macrófagos
Macrophages
RNA-Seq
RNA-Seq
Tuberculosis
https://id.nlm.nih.gov/mesh/D054884
https://id.nlm.nih.gov/mesh/D009169
https://id.nlm.nih.gov/mesh/D008264
https://id.nlm.nih.gov/mesh/D000081246
https://id.nlm.nih.gov/mesh/D014376

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/