Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer's Disease Mutations
ABSTRACT: Alzheimer's disease manifests itself in brain tissue by neuronal death, due to aggregation of β-amyloid, produced by senile plaques, and hyperphosphorylation of the tau protein, which produces neurofibrillary tangles. One of the genetic markers of the disease is the gene that translat...
- Autores:
-
Soto Ospina, Johnny Alejandro
Bedoya Berrío, Gabriel de Jesús
Villegas Lanau, Carlos Andrés
Araque Marín, Pedronel
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2021
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/41092
- Acceso en línea:
- https://hdl.handle.net/10495/41092
- Palabra clave:
- Enfermedad de Alzheimer
Alzheimer Disease
Presenilina-2
Presenilin-2
https://id.nlm.nih.gov/mesh/D000544
https://id.nlm.nih.gov/mesh/D053766
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by/4.0/