In vitro and in silico evaluation of antiretrovirals against SARS-CoV-2: A drug repurposing approach

Abstract: Background: Drug repurposing is a valuable strategy for rapidly developing drugs for treating COVID-19. This study aimed to evaluate the antiviral effect of six antiretrovirals against SARS-CoV-2 in vitro and in silico. Methods: The cytotoxicity of lamivudine, emtricitabine, tenofovir, aba...

Full description

Autores:

Zapata Cardona, María Isabel
Flórez Álvarez, Lizdany
Guerra Sandoval, Ariadna Lucia
Medina Chvatal, Mateo
Guerra Almonacid, Carlos Martín
Hincapié García, Jaime Alejandro
Hernández López, Juan Carlos
Rugeles López, María Teresa
Zapata Builes, Wildeman

Tipo de recurso:

Article of investigation

Fecha de publicación:

2023

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/35476

Acceso en línea:

https://hdl.handle.net/10495/35476

Palabra clave:

SARS-CoV-2
Antirretrovirales
Anti-Retroviral Agents
Tratamiento Farmacológico de COVID-19
COVID-19 Drug Treatment
Simulación del Acoplamiento Molecular
Molecular Docking Simulation
Reposicionamiento de Medicamentos
Drug Repositioning
Enfermedades Transmisibles
Communicable Diseases

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/