Striatal Amyloid is Associated with Tauopathy and Memory Decline in Familial Alzheimer's Disease

ABSTRACT: Background: Autosomal dominant Alzheimer’s disease (ADAD) is distinguished from late-onset AD by early striatal amyloid-β deposition. To determine whether striatal Pittsburgh compound B (PiB)-PET measurements of amyloid-β can help predict disease severity in ADAD, we compared relationships...

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Autores:: Lopera Restrepo, Francisco Javier
Hanseeuw, Bernard J.
Sperling, Reisa A.
Norton, Daniel J.
Guzman Velez, Edmarie
Baena, Ana
Pardilla Delgado, Enmanuelle
Schultz, Aaron P.
Gatchel, Jennifer
Jin, David
Chein, Kewei
Reiman, Eric M.
Johnson, Keith A.
Quiroz, Yakeel T.

Tipo de recurso:: Article of investigation

Fecha de publicación:: 2019

Institución:: Universidad de Antioquia

Repositorio:: Repositorio UdeA

Idioma:: eng