Excess complement activation is associated with adverse outcomes in women with hypertensive disorders of pregnancy

ABSTRACT: Objective Complement activation occurs in normal pregnancy, but excess activation is associated with preeclampsia. Terminal complement activation generates C5b-9, the lytic membrane attack complex, which mediates organ damage. We hypothesize that activation of C5b-9 is increased in women w...

Full description

Autores:

Velásquez Penagos, Jesús Arnulfo
Burwick, Richard
Valencia, Catalina
Vargas Rodríguez, Johanna Celina
Silva, Jaime
Edna Estrada, Francisco
Gutiérrez Marín, Jorge Hernán
Trujillo Otálvaro, Juliana Marcela
Gómez, Ana
Rincón, Mónica
Cabas, Carlos
Quintero, Álvaro
González, Nataly
Lenis Ballesteros, Viviana
Tolosa Ardila, Jorge Enrique

Tipo de recurso:

Article of investigation

Fecha de publicación:

2018

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/37235

Acceso en línea:

https://hdl.handle.net/10495/37235

Palabra clave:

Activación de Complemento
Complement Activation
Preeclampsia
Pre-Eclampsia
Complejo de Ataque a Membrana del Sistema Complemento
Complement Membrane Attack Complex

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/