Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst

ABSTRACT: We studied the effects of Amphotericin B (AmB) on Cryptococcus neoformans using different viability methods (CFUs enumeration, XTT assay and propidium iodide permeability). After 1 h of incubation, there were no viable colonies when the cells were exposed to AmB concentrations 1 mg/L. In t...

Full description

Autores:

Mesa Arango, Ana Cecilia
Casas, Celia
Cuenca Estrella, Manuel
Gianinni Soares Mendes, María José
Herrero, Enrique
Rodríguez Tudela, Juan Luis
Sangalli Leite, Fernanda
Scorzoni, Liliana
Zaragoza, Oscar

Tipo de recurso:

Article of investigation

Fecha de publicación:

2011

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/41217

Acceso en línea:

https://hdl.handle.net/10495/41217

Palabra clave:

Anfotericina B
Amphotericin B
Antifúngicos
Antifungal Agents
Membrana Celular
Cell Membrane
Recuento de Colonia Microbiana
Colony Count, Microbial
Cryptococcus neoformans
Pruebas de Sensibilidad Microbiana
Microbial Sensitivity Tests
Oxidación-Reducción
Oxidation-Reduction
Propidio
Propidium
Estallido Respiratorio
Respiratory Burst
https://id.nlm.nih.gov/mesh/D000666
https://id.nlm.nih.gov/mesh/D000935
https://id.nlm.nih.gov/mesh/D002462
https://id.nlm.nih.gov/mesh/D015169
https://id.nlm.nih.gov/mesh/D003455
https://id.nlm.nih.gov/mesh/D008826
https://id.nlm.nih.gov/mesh/D010084
https://id.nlm.nih.gov/mesh/D011419
https://id.nlm.nih.gov/mesh/D016897

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc/2.5/co/