Phenotypic and Functional Profiles of Antigen-Specific CD4+ and CD8+ T Cells Associated with Infection Control in Patients with Cutaneous Leishmaniasis

ABSTRACT: The host immunological response is a key factor determining the pathogenesis of cutaneous leishmaniasis. It is known that a Th1 cellular response is associated with infection control and that antigen-specific memory T cells are necessary for the development of a rapid and strong protective...

Full description

Autores:
Robledo Restrepo, Sara María
Ledesma, Darién
Pérez Antón, Elena
Montoya, Andrés
Gómez, Inmaculada
Egui Machado, Adriana
Infante, Juan José
Vélez Bernal, Ivan Darío
López, Manuel Carlos
Thomas, Carmen
Tipo de recurso:
Article of investigation
Fecha de publicación:
2018
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/35166
Acceso en línea:
https://hdl.handle.net/10495/35166
Palabra clave:
Leishmania
Leishmaniasis
Biomarkers
Biomarcadores
Phenotype
Fenotipo
Receptors, KIR
Receptores KIR
Th1-Th2 Balance
Balance Th1 - Th2
CD4-CD8 Ratio
Relación CD4-CD8
Rights
openAccess
License
https://creativecommons.org/licenses/by/4.0/