Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome - wide association studies

ABSTRACT: The genome-wide distribution of linkage disequilibrium (LD) determines the strategy for selecting markers for association studies, but it varies between populations. We assayed LD in large samples (200 individuals) from each of 11 well-described population isolates and an outbred European-...

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Autores:

Bedoya Berrio, Gabriel De Jesus
Ruiz Linares, Andrés
Service, Susan
Deyoung, Joseph
Karayiorgou, María
Pretoriuos, Herman
Bedoya, Gabriel
Ospina Duque, Jorge
Macedo, António
Palha, Joana Almeida
Heutink, Peter
Aulchenko, Yurii
Oostra, Ben
Van Duijn, Cornelia
Jarvelin, Marjo Riitta
Varilo, Teppo
Peddle, Lynette
Rahman, Proton
Murray, Sarah
Galver, Luana
Peltonen, Leena
Sabatti, Chiara
Collins, Andrew
Freimer, Nelson

Tipo de recurso:

Article of investigation

Fecha de publicación:

2006

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/36450

Acceso en línea:

https://hdl.handle.net/10495/36450

Palabra clave:

Cromosomas Humanos Par 22
Chromosomes, Human, Pair 22
Genética de Población
Genetics, Population
Genoma Humano
Genome, Human
Desequilibrio de Ligamiento
Linkage Disequilibrium
Polimorfismo de Nucleótido Simple
Polymorphism, Single Nucleotide

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/