Antibody-Dependent Enhancement of Dengue Virus Infection in Primary Human Macrophages; Balancing Higher Fusion against Antiviral Responses
ABSTRACT: The dogma is that the human immune system protects us against pathogens. Yet, several viruses, like dengue virus, antagonize the hosts’ antibodies to enhance their viral load and disease severity; a phenomenon called antibody-dependent enhancement of infection. This study offers novel insi...
- Autores:
-
Diosa Toro, Mayra Alejandra
Hoornweg, Tabitha
Urcuqui Inchima, Silvio
Van de Pol, Denise
Smit, Jolanda M.
Flipse, Jacky
- Tipo de recurso:
- Investigation report
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/36546
- Acceso en línea:
- https://hdl.handle.net/10495/36546
- Palabra clave:
- Anticuerpos Antivirales
Antibodies, Viral
Células Cultivadas
Cells, Cultured
Dengue
Perfilación de la Expresión Génica
Gene Expression Profiling
Interferón Tipo I
Interferon Type I
Macrófagos -efectos de los fármacos
Macrophages - drug effects
Carga Viral
Viral Load
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by/4.0/