It only takes one to do many jobs : Amphotericin B as antifungal and immunomodulatory drug

ABSTRACT “Amphotericin B acts through pore formation at the cell membrane after binding to ergosterol” is an accepted dogma about the action mechanism of this antifungal, and this sentence is widely found in the literature. But after 60 years of investigation, the action mechanism of Amphotericin B...

Full description

Autores:

Mesa Arango, Ana Cecilia
Scorzoni, Liliana
Zaragoza Hernández, Oscar

Tipo de recurso:

Review article

Fecha de publicación:

2012

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/33965

Acceso en línea:

https://hdl.handle.net/10495/33965
https://www.frontiersin.org/articles/10.3389/fmicb.2012.00286/full

Palabra clave:

Amphotericin B
Anfotericina B
Immunomodulation
Inmunomodulación
Mycoses
Micosis
Mitochondrial Permeability Transition Pore
Poro de Transición de la Permeabilidad Mitocondrial
Oxidative Stress
Estrés Oxidativo

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/