Human cells and cell membrane molecular models are affected in vitro by the nonsteroidal anti-inflammatory drug ibuprofen
ABSTRACT: This report presents evidence that ibuprofen interacts with red cell membranes as follows: a) in scanning electron microscopy (SEM) studies on human erythrocytes induced shape changes at a concentration as low as 10μM; b) in isolated unsealed human erythrocyte membranes (IUM) induced mild...
- Autores:
-
Manrique Moreno, Marcela María
Villena, Fernando
P. Sotomayor, Carlos
Edwards, Ana M.
Muñoz, Marcelo A.
Garidel, Patrick
Suwalsky, Mario
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2011
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/34485
- Acceso en línea:
- https://hdl.handle.net/10495/34485
- Palabra clave:
- Anti-Inflammatory Agents, Non-Steroidal
Antiinflamatorios no Esteroideos
Cell membrane
Membrana Celular
Calorimetry, Differential Scanning
Rastreo Diferencial de Calorimetría
Ibuprofen
Ibuprofeno
Cell Line, Tumor
Línea Celular Tumoral
Dimyristoylphosphatidylcholine
Dimiristoilfosfatidilcolina
Erythrocytes - drug effects
Eritrocitos - efectos de los fármacos
Microscopy, Electron, Scanning
Microscopía Electrónica de Rastreo
Models, Molecular
Modelos Moleculares
Unilamellar Liposomes
Liposomas Unilamelares
X-Ray Diffraction
Difracción de Rayos X
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/