State of Artemisinin and Partner Drug Susceptibility in Plasmodium falciparum Clinical Isolates from Colombia

ABSTRACT: Delayed parasite clearance time observed in Southeast Asia provided the first evidence of Plasmodium falciparum resistance to artemisinins. The ex vivo ring-stage survival assay (RSA) mimics parasite exposure to pharmacologically relevant artemisinin concentrations. Mutations in the C-term...

Full description

Autores:

Montenegro Cadena, Lidia Madeline
de Las Salas Calderón, Briegel
Tobón Castaño, Alberto
Lopera Mesa, Tatiana María
Fairhurst, Rick M.
Neal, Aaron T.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2021

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/42051

Acceso en línea:

https://hdl.handle.net/10495/42051

Palabra clave:

Antimaláricos
Antimalarials
Resistencia a Medicamentos
Drug Resistance
Malaria Falciparum
Malaria, Falciparum
Plasmodium falciparum
Proteínas Asociadas a Resistencia a Múltiples Medicamentos
Multidrug Resistance-Associated Proteins
Reacción en Cadena de la Polimerasa
Polymerase Chain Reaction
Colombia - epidemiología
Colombia - epidemiology
https://id.nlm.nih.gov/mesh/D000962
https://id.nlm.nih.gov/mesh/D004351
https://id.nlm.nih.gov/mesh/D016778
https://id.nlm.nih.gov/mesh/D010963
https://id.nlm.nih.gov/mesh/D027425
https://id.nlm.nih.gov/mesh/D016133
https://id.nlm.nih.gov/mesh/D003105

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/