Broad-spectrum Antibodies Against self-antigens and Cytokines in RAG Deficiency

ABSTRACT: Patients with mutations of the recombination-activating genes (RAG) present with diverse clinical phenotypes, including severe combined immune deficiency (SCID), autoimmunity, and inflammation. However, the incidence and extent of immune dysregulation in RAG-dependent immunodeficiency have...

Full description

Autores:

Franco Restrepo, José Luis
Walter, Jolan E.
Rosen, Lindsey B.
Csomos, Krisztian
Rosenberg, Jacob M.
Mathew, Divij
Keszei, Marton
Ujhazi, Boglarka
Chen, Karin
Lee, Yu Nee
Tirosh, Irit
Dobbs, Kerry
Al-Herz, Waleed
Cowan, Morton J.
Puck, Jennifer
Bleesing, Jack J.
Grimley, Michael S.
Malech, Harry
De Ravin, Suk See
Gennery, Andrew R.
Abraham, Roshini S.
Joshi, Avni Y.
Boyce, Thomas G.
Butte, Manish J.
Nadeau, Kari C.
Balboni, Imelda
Sullivan, Kathleen E.
Akhter, Javeed
Adeli, Mehdi
El-Feky, Reem A.
El-Ghoneimy, Dalia H.
Dbaibo, Ghassan
Wakim, Rima
Azzari, Chiara
Palma, Paolo
Cancrini, Caterina
Capuder, Kelly
Condino Neto, Antonio
Costa Carvalho, Beatriz T.
Bosco Oliveira, Joao Bosco
Roifman, Chaim
Buchbinder, David
Kumanovics, Attila
Niehues, Tim
Niehues, Tim
Schuetz, Catharina
Kuijpers, Taco
Yee, Christina
Chou, Janet
Masaad, Michel J.
Geha, Raif
Uzel, Gulbu
Gelman, Rebecca
Holland, Steven M.
Recher, Mike
Utz, Paul J.
Browne, Sarah K.
Notarangelo, Luigi D.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2015

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/34627

Acceso en línea:

https://hdl.handle.net/10495/34627

Palabra clave:

Broadly Neutralizing Antibodies
Anticuerpos ampliamente neutralizantes
Autoantigens
Autoantígenos
Cytokines
Citocinas
Autoimmunity
Autoinmunidad
Severe Combined Immunodeficiency
Inmunodeficiencia Combinada Grave

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/