Coprocessed excipients with enhanced direct compression functionality for improved tableting performance

ABSTRACT: It is necessary to have excipients with excellent functional properties to compensate for the poor mechanical properties and low aqueous solubility of the emerging active ingredients. Therefore, around 80% of the current drugs are not suitable for direct compression and more advanced excip...

Full description

Autores:

Rojas Camargo, John Jairo
Buckmer, Ira
Kumar, Vijay

Tipo de recurso:

Review article

Fecha de publicación:

2012

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/35418

Acceso en línea:

https://hdl.handle.net/10495/35418

Palabra clave:

Química Farmacéutica - métodos
Chemistry, Pharmaceutical - methods
Fuerza Compresiva
Compressive Strength
Excipientes - Química
Excipients - Chemistry
Tamaño de la Partícula
Particle Size
Polvos - Química
Powders - Chemistry
Solubilidad
Solubility
Comprimidos - Química
Tablets - Chemistry
Tecnología Farmacéutica - métodos
Technology, Pharmaceutical - methods

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/