Synthetic inhibitors of snake venom enzymes: Thioesters derived from 2-sulfenyl ethylacetate

ABSTRACT: Snakebite envenomings are a global public health issue. The therapy based on the administration of animal-derived antivenoms has limited efficacy against the venom-induced local tissue damage, which often leads to permanent disability. Therefore, there is a need to find inhibitors against...

Full description

Autores:
Henao Castañeda, Isabel Cristina
Pereañez Jiménez, Jaime Andrés
Preciado Rojo, Lina María
Tipo de recurso:
Article of investigation
Fecha de publicación:
2019
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/39533
Acceso en línea:
https://hdl.handle.net/10495/39533
Palabra clave:
Mordeduras de Serpientes
Snake Bites
Fosfolipasas A2
Phospholipases A2
Simulación del Acoplamiento Molecular
Molecular Docking Simulation
Tioéster
Thioester
Snake venom metalloproteinase
https://id.nlm.nih.gov/mesh/D012909
https://id.nlm.nih.gov/mesh/D054467
https://id.nlm.nih.gov/mesh/D062105
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/