Elevated non-esterified fatty acid concentrations during in vitro murine follicle growth alter follicular physiology and reduce oocyte developmental competence

ABSTRACT: Objective: To study how long-term elevated non-esterified fatty acid (NEFA) concentrations, typical in metabolic disorders such as obesity or type 2 diabetes, affect murine follicular development, follicle quality, and subsequent oocyte developmental competence in vitro. Design: Experiment...

Full description

Autores:

López Cardona, Ángela Patricia
M. Valckx, Sara D.
Hoeck, Veerle Van
Arias Álvarez, María
Maillo, Verónica
Gutiérrez Adan, Alfonso
Berth, Mario
Cortvrindt, Rita
J. Bols, Peter E.
R. Leroy, Jo L. M.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2014

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/34675

Acceso en línea:

https://hdl.handle.net/10495/34675

Palabra clave:

Células Cultivadas
Cells, Cultured
Ácidos Grasos no Esterificados - metabolismo
Fatty Acids, Nonesterified - metabolism
Obesidad
Obesity
Inhibinas - biosíntesis
Inhibins - biosynthesis
Ratones
Mice
Oocitos - fisiología
Oocytes - physiology
Folículo Ovárico
Ovarian Follicle
Ovulación
Ovulation
Progesterona - biosíntesis
Progesterone - biosynthesis

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/