MicroRNA profiling of human primary macrophages exposed to dengue virus identifies miRNA-3614-5p as antiviral and regulator of ADAR1 expression

ABSTARCT: Due to the high burden of dengue disease worldwide, a better understanding of the interactions between dengue virus (DENV) and its human host cells is of the utmost importance. Although microRNAs modulate the outcome of several viral infections, their contribution to DENV replication is po...

Full description

Autores:

Diosa Toro, Mayra Alejandra
Fernández García, Geysson Javier
Urcuqui Inchima, Silvio
Echavarría Consuegra, Liliana
Kluiver, Joost
Van den Berg, Anke
Flipse, Jacky
Smit, Jolanda

Tipo de recurso:

Article of investigation

Fecha de publicación:

2017

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/11996

Acceso en línea:

http://hdl.handle.net/10495/11996

Palabra clave:

Adenosine Deaminase
Dengue Virus
Gene Deletion
Gene Expression Regulation
Macrophages
metabolism
MicroRNAs
RNA-Binding Proteins
Transcriptome
Virus Replication

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/