Linkage Disequilibrium and Haplotype Homozygosity in Population Samples Genotyped at a High Marker Density

ABSTRACT: Objective: Analyze the information contained in homozygous haplotypes detected with high density genotyping. Methods: We analyze the genotypes of ∼2,500 markers on chr 22 in 12 population samples, each including 200 individuals. We develop a measure of disequilibrium based on haplotype hom...

Full description

Autores:

Bedoya Berrío, Gabriel de Jesús
Lin, Chia-Ho
Service, Susan
Chen, Yuguo
Freimer, Nelson
Sabatti, Chiara
Wang, Hui
Ospina Duque, Jorge

Tipo de recurso:

Article of investigation

Fecha de publicación:

2006

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/41530

Acceso en línea:

https://hdl.handle.net/10495/41530

Palabra clave:

Consanguinidad
Consanguinity
Cromosomas Humanos Par 22
Chromosomes, Human, Pair 22
Frecuencia de los Genes
Gene Frequency
Marcadores Genéticos
Genetic Markers
Cadenas de Markov
Markov Chains
Homocigoto
Homozygote
https://id.nlm.nih.gov/mesh/D003241
https://id.nlm.nih.gov/mesh/D002892
https://id.nlm.nih.gov/mesh/D005787
https://id.nlm.nih.gov/mesh/D005819
https://id.nlm.nih.gov/mesh/D008390
https://id.nlm.nih.gov/mesh/D006720

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc/4.0/