Predisposition to accelerated Alzheimer-related changes in the brains of human immunodeficiency virus negative opiate abusers

ABSTRACT: Cognitive impairment is a recognized effect of drug misuse, including the use of opiates. The pathological basis for this is unknown but the temporal and frontal cortices have been implicated. We have shown previously that deposits of hyperphosphorylated tau in drug user brains exceed thos...

Full description

Autores:

Arango Viana, Juan Carlos
Bell, Jeanne E.
Robertson, Roy
Millar, Tracey
Anthony, Iain C.
Norrby, Katherine E.
Dingwall, Tommy
Carnie, Frances W.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2010

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43589

Acceso en línea:

https://hdl.handle.net/10495/43589

Palabra clave:

Enfermedad de Alzheimer
Alzheimer Disease
Péptidos beta-Amiloides
Amyloid beta-Peptides
Apolipoproteínas E
Apolipoproteins E
Barrera Hematoencefálica
Blood-Brain Barrier
Western Blotting
Blotting, Western
Encéfalo
Brain
Progresión de la Enfermedad
Disease Progression
Encefalitis
Encephalitis
Glucógeno Sintasa Quinasa 3
Glycogen Synthase Kinase 3
Inmunohistoquímica
Immunohistochemistry
Trastornos Relacionados con Opioides
Opioid-Related Disorders
Fosforilación
Phosphorylation
Proteínas tau
tau Proteins
https://id.nlm.nih.gov/mesh/D000544
https://id.nlm.nih.gov/mesh/D016229
https://id.nlm.nih.gov/mesh/D001057
https://id.nlm.nih.gov/mesh/D001812
https://id.nlm.nih.gov/mesh/D015153
https://id.nlm.nih.gov/mesh/D001921
https://id.nlm.nih.gov/mesh/D018450
https://id.nlm.nih.gov/mesh/D004660
https://id.nlm.nih.gov/mesh/D038362
https://id.nlm.nih.gov/mesh/D007150
https://id.nlm.nih.gov/mesh/D009293
https://id.nlm.nih.gov/mesh/D010766
https://id.nlm.nih.gov/mesh/D016875

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc/2.5/co/