Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates

ABSTRACT: Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP) in numerous multigenerational pedig...

Full description

Autores:

Bedoya Berrío, Gabriel de Jesús
Gómez Makhinson, Juliana
López Tobón, María Cecilia
Montoya Montoya, Gabriel Jaime
Montoya Guerra, Claudia Patricia
Ospina Duque, Jorge
López Jaramillo, Carlos Alberto
Ruíz Linares, Andrés
Ori, Anil P S
Zhang, Zhongyang
Mullins, Niamh
Olde Loohuis, Loes M
Fears, Scott C
Araya, Carmen
Araya, Xinia
Spesny, Mitzi
Bejarano, Julio
Ramírez, Margarita
Castrillón, Gabriel
Hoon Sul, Jae
Service, Susan K.
Huang, Alden Y.
Ramensky, Vasily
Aldana, Ileana
Escobar, Javier I.
Hwang, Sun-Goo
Kremeyer, Barbara
Park, YoungJun
Cantor, Rita M.
Molina, Julio
Coppola, Giovanni
Ophoff, Roel A.
Macaya, Gabriel
Teshiba, Terri M.
Reus, Víctor
Bearden, Carrie E.
Sabatti, Chiara
Freimer, Nelson B.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/41112

Acceso en línea:

https://hdl.handle.net/10495/41112

Palabra clave:

Bipolar Disorder
Trastorno Bipolar
Genetic Predisposition to Disease
Predisposición Genética a la Enfermedad
Genome-Wide Association Study
Estudio de Asociación del Genoma Completo
Polymorphism, Single Nucleotide
Polimorfismo de Nucleótido Simple
Pedigree
Linaje
https://id.nlm.nih.gov/mesh/D001714
https://id.nlm.nih.gov/mesh/D020022
https://id.nlm.nih.gov/mesh/D055106
https://id.nlm.nih.gov/mesh/D020641
https://id.nlm.nih.gov/mesh/D010375

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/