Heterologous expression and immunogenic potential of the most abundant phospholipase A2 from coral snake micrurus dumerilii to develop antivenoms

ABSTRACT: Micrurus dumerilii is a coral snake of clinic interest in Colombia. Its venom is mainly composed of phospholipases A2 being MdumPLA2 the most abundant protein. Nevertheless, Micrurus species produce a low quantity of venom, which makes it difficult to produce anticoral antivenoms. Therefor...

Full description

Autores:

Romero Giraldo, Luz Elena
Pulido Muñoz, Sergio Andrés
Berrío, Mario A.
Flórez González, María Fernanda
Rey Suárez, Jessica Paola
Núñez Rangel, Vitelbina
Pereañez Jiménez, Jaime Andrés

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/41406

Acceso en línea:

https://hdl.handle.net/10495/41406

Palabra clave:

Antivenenos
Antivenins
Serpientes de Coral
Coral Snakes
Venenos Elapídicos - enzimología
Elapid Venoms - enzymology
Ratones
Mice
Fosfolipasas A2
Phospholipases A2
Conejos
Rabbits
Proteínas Recombinantes
Recombinant Proteins
https://id.nlm.nih.gov/mesh/D000997
https://id.nlm.nih.gov/mesh/D000073181
https://id.nlm.nih.gov/mesh/D004546
https://id.nlm.nih.gov/mesh/D051379
https://id.nlm.nih.gov/mesh/D054467
https://id.nlm.nih.gov/mesh/D011817
https://id.nlm.nih.gov/mesh/D011994

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/