Changes in beta 2-adrenoceptor and other signaling proteins produced by chronic administration of 'beta-blockers' in a murine asthma model

ABSTRACT: Background—We have previously reported that chronic treatment with certain ‘β-blockers’ reduces airway hyperresponsiveness (AHR) to methacholine in a murine model of asthma. Methods—Airway resistance was measured using the forced oscillation technique in ovalbulmin-sensitized and ovalbulmi...

Full description

Autores:

Parra, Sergio
Bond, Richard A.
Shardonofsky, Felix
Knoll, Brian J.
Peng, Hui
Nguyen, Long P.
Dudekula, Noor
Lin, Rui

Tipo de recurso:

Article of investigation

Fecha de publicación:

2007

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/38205

Acceso en línea:

https://hdl.handle.net/10495/38205

Palabra clave:

Antagonistas Adrenérgicos beta - administración & dosificación
Adrenergic beta-Antagonists - administration & dosage
Antagonistas Adrenérgicos beta - farmacología
Adrenergic beta-Antagonists - pharmacology
Resistencia de las Vías Respiratorias - efectos de los fármacos
Airway Resistance - drug effects
Animales
Animals
Asma
Asthma
Western Blotting
Blotting, Western
Pruebas de Provocación Bronquial
Bronchial Provocation Tests
Esquema de Medicación
Drug Administration Schedule
Técnica del Anticuerpo Fluorescente
Fluorescent Antibody Technique
Péptidos y Proteínas de Señalización Intracelular - metabolismo
Intracellular Signaling Peptides and Proteins - metabolism
Cloruro de Metacolina
Methacholine Chloride
Metoprolol - administración & dosificación
Metoprolol - administration & dosage
Metoprolol - farmacología
Metoprolol - farmacología
Ratones
Mice
Ratones Endogámicos BALB C
Mice, Inbred BALB C
Nadolol - farmacología
Nadolol - pharmacology
Ovalbúmina - inmunología
Ovalbumin - immunology
Propanolaminas - administración & dosificación
Propanolamines - administration & dosage
Propanolaminas - farmacología
Propanolamines - pharmacology
Receptores Adrenérgicos beta 2 - metabolismo
Receptors, Adrenergic, beta-2 - metabolism
https://id.nlm.nih.gov/mesh/D016210
https://id.nlm.nih.gov/mesh/D008790
https://id.nlm.nih.gov/mesh/D000319
https://id.nlm.nih.gov/mesh/D000403
https://id.nlm.nih.gov/mesh/D000818
https://id.nlm.nih.gov/mesh/D001249
https://id.nlm.nih.gov/mesh/D015153
https://id.nlm.nih.gov/mesh/D001985
https://id.nlm.nih.gov/mesh/D004334
https://id.nlm.nih.gov/mesh/D005455
https://id.nlm.nih.gov/mesh/D047908
https://id.nlm.nih.gov/mesh/D051379
https://id.nlm.nih.gov/mesh/D008807
https://id.nlm.nih.gov/mesh/D009248
https://id.nlm.nih.gov/mesh/D010047
https://id.nlm.nih.gov/mesh/D011412
https://id.nlm.nih.gov/mesh/D018343

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/