Reformulating Small Molecules for Cardiovascular Disease Immune Intervention: Low-Dose Combined Vitamin D/Dexamethasone Promotes IL-10 Production and Atheroprotection in Dyslipidemic Mice

ABSTRACT: The targeting of proinflammatory pathways has a prophylactic and therapeutic potential on atherosclerotic cardiovascular diseases (CVD). An alternative/complementary strategy is the promotion of endogenous atheroprotective mechanisms that are impaired during atherosclerosis progression, su...

Full description

Autores:

Ospina Quintero, Leidy Laura
Jaramillo Alzate, Julio Cesar
Tabares Guevara, Jorge Humberto
Ramírez Pineda, José Robinson

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/45571

Acceso en línea:

https://hdl.handle.net/10495/45571

Palabra clave:

Apolipoproteins E
Apolipoproteínas E
Atherosclerosis
Aterosclerosis
CD8-Positive T-Lymphocytes
Linfocitos T CD8-positivos
Cardiovascular Diseases
Enfermedades Cardiovasculares
Dexamethasone
Dexametasona
Interferon-gamma
Interferón gamma
Interleukin-10
Interleucina-10
Mice, Inbred BALB C
Ratones Endogámicos BALB C
Mice, Inbred C57BL
Ratones Endogámicos C57BL
T-Lymphocytes, Regulatory
Linfocitos T Reguladores
Vitamin D
Vitamina D
https://id.nlm.nih.gov/mesh/D001057
https://id.nlm.nih.gov/mesh/D050197
https://id.nlm.nih.gov/mesh/D018414
https://id.nlm.nih.gov/mesh/D002318
https://id.nlm.nih.gov/mesh/D003907
https://id.nlm.nih.gov/mesh/D007371
https://id.nlm.nih.gov/mesh/D016753
https://id.nlm.nih.gov/mesh/D008807
https://id.nlm.nih.gov/mesh/D008810
https://id.nlm.nih.gov/mesh/D050378
https://id.nlm.nih.gov/mesh/D014807

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/