Differential effects of oleate on vascular endothelial and liver sinusoidal endothelial cells reveal its toxic features in vitro

ABSTRACT: Several fatty acids, in particular saturated fatty acids like palmitic acid, cause lipotoxicity in the context of non-alcoholic fatty liver disease . Unsaturated fatty acids (e.g. oleic acid) protect against lipotoxicity in hepatocytes. However, the effect of oleic acid on other liver cell...

Full description

Autores:

Arroyave Ospina, Johanna Carolina
Geng, Yana
Buist Homan, Manon
Plantinga, Josée
Olinga, Peter
Reijngoud, Dirk Jan
Van Vilsteren, Frederike G. I.
Blokzijl, Hans
Kamps, Jan A. A. M.
Moshage, Han

Tipo de recurso:

Investigation report

Fecha de publicación:

2023

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39593

Acceso en línea:

https://hdl.handle.net/10495/39593

Palabra clave:

Ácidos Grasos
Fatty Acids
Metabolismo
Metabolism
Hepatocitos
Hepatocytes
Células Endoteliales de la Vena Umbilical Humana
Human Umbilical Vein Endothelial Cells
Ácido Oléico
Oleic Acid
Farmacología
Pharmacology
Palmitatos
Palmitates
Ácido Palmítico
Palmitic Acid
https://id.nlm.nih.gov/mesh/D005227
https://id.nlm.nih.gov/mesh/D008660
https://id.nlm.nih.gov/mesh/D022781
https://id.nlm.nih.gov/mesh/D061307
https://id.nlm.nih.gov/mesh/D019301
https://id.nlm.nih.gov/mesh/D010600
https://id.nlm.nih.gov/mesh/D010168
https://id.nlm.nih.gov/mesh/D019308

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/