Human Proteinase 3, an important autoantigen of c-ANCA associated vasculitis, shares cross-reactive epitopes with serine protease allergens from mites: an in silico analysis

ABSTRACT: Background: In autoimmune vasculitis, autoantibodies to Human Proteinase 3 (PR3), a human serine protease, seems to have a role on the inception of c-ANCA associated vasculitis. The origin of this autoreactive response remains unclear. However, for several autoreactive responses, molecular...

Full description

Autores:

Buendía Dávila, Emiro Rafael
Múnera Gómez, Marlon Gustavo
Parra, Orlando
Sánchez Solano, María Alejandra
Sánchez Caraballo, Andrés
Sánchez Caraballo, Jorge Mario
Viasus Pérez, Diego Fernando

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/45007

Acceso en línea:

https://hdl.handle.net/10495/45007

Palabra clave:

Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Anticuerpos Anticitoplasma de Neutrófilos
Antibodies, Antineutrophil Cytoplasmic
Epítopos de Linfocito B
Epitopes, B-Lymphocyte
Epitopes, T-Lymphocyte
Alérgenos
Allergens
Autoantígenos
Autoantigens
Serina Proteasas
Serine Proteases
Mieloblastina
Myeloblastin
Pyroglyphidae
Reacciones Cruzadas
Cross Reactions
https://id.nlm.nih.gov/mesh/D056648
https://id.nlm.nih.gov/mesh/D019268
https://id.nlm.nih.gov/mesh/D018985
https://id.nlm.nih.gov/mesh/D018984
https://id.nlm.nih.gov/mesh/D000485
https://id.nlm.nih.gov/mesh/D001324
https://id.nlm.nih.gov/mesh/D057057
https://id.nlm.nih.gov/mesh/D053146
https://id.nlm.nih.gov/mesh/D039981
https://id.nlm.nih.gov/mesh/D003429

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/