The Role of Spike Protein Mutations in the Infectious Power of SARS-COV-2 Variants: A Molecular Interaction Perspective

ABSTRACT: Specific S477N, N501Y, K417N, K417T, E484K mutations in the receptor binding domain (RBD) of the spike protein in the wild type SARS-COV-2 virus have resulted, among others, in the following variants: B.1.160 (20A or EU2, first reported in continental Europe), B1.1.7 (α or 20I501Y.V1, firs...

Full description

Autores:

Agudelo Gómez, Santiago
Rojas Valencia, Natalia Andrea
Restrepo Cossio, Albeiro Alonso
Gómez, Sara
Cappelli, Chiara

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/41664

Acceso en línea:

https://hdl.handle.net/10495/41664

Palabra clave:

COVID-19
Mutación
Mutation
Unión Proteica - genética
Protein Binding - genetics
SARS-CoV-2 - genética
SARS-CoV-2 - genetics
Glicoproteína de la Espiga del Coronavirus
Spike Glycoprotein, Coronavirus - chemistry - química
https://id.nlm.nih.gov/mesh/D000086382
https://id.nlm.nih.gov/mesh/D009154
https://id.nlm.nih.gov/mesh/D011485
https://id.nlm.nih.gov/mesh/D000086402
https://id.nlm.nih.gov/mesh/D064370

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/