Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids

ABSTRACT: Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively. Structures of the products were elucidated by spectroscopic analysis. The synthesized compou...

Full description

Autores:

Otero Tejada, Elver Luis
Vergara Guiral, Sebastian
Robledo Restrepo, Sara María
Cardona Galeano, Wilson
Carda Usó, Pedro Miguel
Vélez Bernal, Iván Darío
Rojas Arbeláez, Carlos Alberto
Otálvaro Tamayo, Felipe

Tipo de recurso:

Article of investigation

Fecha de publicación:

2014

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/23678

Acceso en línea:

http://hdl.handle.net/10495/23678

Palabra clave:

Antiprotozoario
Antiprotozoal Agents
Triclosán
Triclosan
Cumarinas
Coumarins
Cromonas
Chromones
Chalcona
Chalcone
Leishmaniosis
Híbrido
Hybrids
http://aims.fao.org/aos/agrovoc/c_35197
http://aims.fao.org/aos/agrovoc/c_3707
https://id.nlm.nih.gov/mesh/D000981
https://id.nlm.nih.gov/mesh/D014260
https://id.nlm.nih.gov/mesh/D003374
https://id.nlm.nih.gov/mesh/D002867
https://id.nlm.nih.gov/mesh/D002599

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/