Decreased miR-497-5p Suppresses IL-6 Induced Atrophy in Muscle Cells

ABSTRACT: Interleukin-6 (IL-6) is a pro-inflammatory cytokine associated with skeletal muscle wasting in cancer cachexia. The control of gene expression by microRNAs (miRNAs) in muscle wasting involves the regulation of thousands of target transcripts. However, the miRNA-target networks associated w...

Full description

Autores:

Fernández García, Geysson Javier
Freire, Paula P.
Cury, Sarah S.
Lopes, Letícia O.
Liu, Jianming
de Moraes, Leonardo Nazario
de Oliveira, Grasieli
Oliveira, Jakeline S
de Moraes, Diogo
Cabral Marques, Otavio
Dal-Pai-Silva, Maeli
Hu, Xiaoyun
Wang, Da-Zhi
Carvalho, Robson F.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2021

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/41090

Acceso en línea:

https://hdl.handle.net/10495/41090

Palabra clave:

Cachexia
Línea Celular
Cell Line
Proliferación Celular
Cell Proliferation
Regulación de la Expresión Génica
Gene Expression Regulation
Insulina
Insulin
Interleucina-6
Interleukin-6
MicroARNs
MicroRNAs
Modelos Biológicos
Models, Biological
Células Musculares
Muscle Cells
Fibras Musculares Esqueléticas
Muscle Fibers, Skeletal
Atrofia Muscular
Muscular Atrophy
Neoplasias
Neoplasms
Receptor IGF Tipo 1
Receptor, IGF Type 1
Reproducibilidad de los Resultados
Reproducibility of Results
Transducción de Señal
Signal Transduction
https://id.nlm.nih.gov/mesh/D002100
https://id.nlm.nih.gov/mesh/D002460
https://id.nlm.nih.gov/mesh/D049109
https://id.nlm.nih.gov/mesh/D005786
https://id.nlm.nih.gov/mesh/D007328
https://id.nlm.nih.gov/mesh/D015850
https://id.nlm.nih.gov/mesh/D035683
https://id.nlm.nih.gov/mesh/D008954
https://id.nlm.nih.gov/mesh/D032342
https://id.nlm.nih.gov/mesh/D018485
https://id.nlm.nih.gov/mesh/D009133
https://id.nlm.nih.gov/mesh/D009369
https://id.nlm.nih.gov/mesh/D017526
https://id.nlm.nih.gov/mesh/D015203
https://id.nlm.nih.gov/mesh/D015398

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/