Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47

ABSTRACT: Suppression of major histocompatibility complex (MHC) class II antigen presentation is believed to be among the major mechanisms used by Mycobacterium tuberculosis to escape protective host immune responses. Through a genome-wide screen for the genetic loci of M. tuberculosis that inhibit...

Full description

Autores:

Baena García, Andres
Saini, Neeraj K.
Ng, Tony W.
Venkataswamy, Manjunatha M.
Kennedy, Steven C.
Kunnath Velayudhan, Shajo
Carreño, Leandro J.
Xu, Jiayong
Chan, John
Larsen, Michelle H.
Jacobs Jr., William R.
Porcelli, Steven A .

Tipo de recurso:

Article of investigation

Fecha de publicación:

2016

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/36759

Acceso en línea:

https://hdl.handle.net/10495/36759

Palabra clave:

Autofagia
Autophagy
Mycobacterium tuberculosis
Antígenos de Histocompatibilidad Clase II
Histocompatibility Antigens Class II
Sitios Genéticos
Genetic Loci
Fagocitos
Phagocytes
Inmunidad Adaptativa
Adaptive Immunity
Proteínas bacterianas
Bacterial Proteins
Ratones Endogámicos C57BL
Mice, Inbred C57BL
Eliminación de Gen
Gene Deletion

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/