HIV-induced T-cell activation/exhaustion in rectal mucosa is controlled only partially by antiretroviral treatment

ABSTRACT: Peripheral blood T-cells from untreated HIV-1-infected patients exhibit reduced immune responses, usually associated with a hyperactivated/exhausted phenotype compared to HAART treated patients. However, it is not clear whether HAART ameliorates this altered phenotype of T-cells in the gas...

Full description

Autores:
Rueda Ríos, Cesar Mauricio
Velilla Hernández, Paula Andrea
Chougnet, Claire
Montoya Guarín, Carlos Julio
Rugeles López, María Teresa
Tipo de recurso:
Article of investigation
Fecha de publicación:
2012
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/36728
Acceso en línea:
https://hdl.handle.net/10495/36728
Palabra clave:
Fármacos Anti-VIH
Anti-HIV Agents
Terapia Antirretroviral Altamente Activa
Antiretroviral Therapy, Highly Active
Linfocitos T CD4-Positivos
CD4-Positive T-Lymphocytes
Antígeno CTLA-4
CTLA-4 Antigen
Infecciones por VIH
HIV Infections
Recto
Rectum
Subunidad alfa del receptor de interleucina-2
Interleukin-2 Receptor alpha Subunit
Tejido Linfoide
Lymphoid Tissue
Membrana mucosa
Mucous Membrane
Receptor de muerte celular programada 1
Programmed Cell Death 1 Receptor
Rights
openAccess
License
https://creativecommons.org/licenses/by/4.0/