Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals

ABSTRACT: Vaccine-mediated immunity often relies on the generation of protective antibodies and memory B cells, which commonly stem from germinal center (GC) reactions. An in-depth comparison of the GC responses elicited by SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals has no...

Full description

Autores:

Castaño Monsalve, Diana María
Lederer, Katlyn
Bettini, Emily
Parvathaneni, Kalpana
Painter, Mark M.
Agarwal, Divyansh
Lundgreen, Kendall A.
Weirick, Madison
Muralidharan, Kavitha
Goel, Rishi R.
Xu, Xiaoming
Drapeau, Elizabeth M.
Gouma, Sigrid
Ort, Jordan T.
Awofolaju, Moses
Greenplate, Allison R.
Coz, Carole Le
Romberg, Neil
Trofe Clark, Jennifer
Malat, Gregory
Locci, Michela

Tipo de recurso:

Article of investigation

Fecha de publicación:

2022

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/40181

Acceso en línea:

https://hdl.handle.net/10495/40181

Palabra clave:

SARS-CoV-2
Células T Auxiliares Foliculares
T Follicular Helper Cells
Biopsia con Aguja Fina
Biopsy, Fine-Needle
Huésped Inmunocomprometido
Immunocompromised Host
Centro Germinal
Germinal Center
Células B de Memoria
Memory B Cells
Anticuerpos Neutralizantes
Antibodies, Neutralizing
Vacunas de ARNm
mRNA Vaccines
https://id.nlm.nih.gov/mesh/D000086402
https://id.nlm.nih.gov/mesh/D000084522
https://id.nlm.nih.gov/mesh/D044963
https://id.nlm.nih.gov/mesh/D016867
https://id.nlm.nih.gov/mesh/D018858
https://id.nlm.nih.gov/mesh/D000091245
https://id.nlm.nih.gov/mesh/D057134
https://id.nlm.nih.gov/mesh/D000087503

Rights

openAccess

License

https://creativecommons.org/licenses/by/4.0/