Janus kinase inhibitors modify the fatty acid profile of extracellular vesicles and modulate the immune response

ABSTRACT: Methods: EVs were isolated from monocytes (M) and lymphocytes (L) of healthy individuals, as well as from U937 (U) and Jurkat (J) cells exposed to non-cytotoxic concentrations of BARI, ITA, and dimethyl sulfoxide (DMSO; vehicle control). The binding to and engulfment of EVs by peripheral b...

Full description

Autores:

Daza Zapata, Ana María
Vásquez Duque, Gloria María
Rojas López, Mauricio
Palacio Betancur, Juliana
Álvarez Díaz, Karen Dayanna

Tipo de recurso:

Article of investigation

Fecha de publicación:

2024

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43144

Acceso en línea:

https://hdl.handle.net/10495/43144

Palabra clave:

Monocitos
Monocytes
Agregación Plaquetaria
Platelet Aggregation
Ácidos Grasos
Fatty Acids
Inhibidores de las Cinasas Janus
Janus Kinase Inhibitors
Inmunidad
Immunity
Linfocitos
Lymphocytes
Vesículas Extracelulares
Extracellular Vesicles
Baricitinib
Itacitinib
https://id.nlm.nih.gov/mesh/D009000
https://id.nlm.nih.gov/mesh/D010974
https://id.nlm.nih.gov/mesh/D005227
https://id.nlm.nih.gov/mesh/D000075242
https://id.nlm.nih.gov/mesh/D007109
https://id.nlm.nih.gov/mesh/D008214
https://id.nlm.nih.gov/mesh/D000067128

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/