Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer's Disease Leads to Neuroglial and Endothelial Cell Degeneration

ABSTRACT: Evidence suggests that extracellular vesicles (EVs) act as mediators and biomarkers of neurodegenerative diseases. Two distinct forms of Alzheimer disease (AD) are known: a late-onset sporadic form (SAD) and an early-onset familial form (FAD). Recently, neurovascular dysfunction and altere...

Full description

Autores:

Aguillón Niño, David Fernando
Villar Vesga, Juan Manuel
Henao Restrepo, Julián Andrés
Posada Duque, Rafael Andrés
Villegas Lanau, Carlos Andrés
Castaño Monsalve, Diana María
Arias Londoño, Julián David
Cardona Gómez, Gloria Patricia
Voshart, Daniëlle C.
Ribovski, Laís
Barazzuol, Lara
Zuhorn, Inge S.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43063

Acceso en línea:

https://hdl.handle.net/10495/43063

Palabra clave:

Enfermedad de Alzheimer
Alzheimer Disease
Endotelio
Endothelium
Vesículas Extracelulares
Extracellular Vesicles
Organoides
Organoids
Leucocitos
Leukocytes
Plaquetas
Blood Platelets
https://id.nlm.nih.gov/mesh/D000544
https://id.nlm.nih.gov/mesh/D004727
https://id.nlm.nih.gov/mesh/D000067128
https://id.nlm.nih.gov/mesh/D009940
https://id.nlm.nih.gov/mesh/D007962
https://id.nlm.nih.gov/mesh/D001792

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/