Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche.

ABSTRACT:Adult hypothalamic neurogenesis has been recently reported, but the cell of origin and function of these newborn neurons are unknown. We utilize genetic fate mapping to show that median eminence tanycytes generate newborn neurons; blocking this neurogenesis alters weight and metabolic activ...

Full description

Autores:

Miranda Angulo, Ana Lucia
Lee, Daniel A.
Bedont, Joseph L.
Pak, Thomas
Wang, Hong
Song, Juan
Takiar, Vani
Charubhumi, Vanessa
Balordi, Francesca
Takebayashi, Hirohide
Aja, Susan
Ford, Eric
Fishell, Gordon
Blackshaw, Seth

Tipo de recurso:

Article of investigation

Fecha de publicación:

2012

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/36725

Acceso en línea:

https://hdl.handle.net/10495/36725

Palabra clave:

Neurogénesis
Hipotálamo
Hypothalamus
Peso corporal
Body Weight
Bromodesoxiuridina
Bromodeoxyuridine
Dieta alta en grases
Diet hight fat
Eminencia Media
Median Eminence
Ratones endogámicos C57BL
Mice, Inbred C57BL
Receptores de estrógeno
Receptors, Estrogen
Tamoxifeno
Tamoxifen

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/