Baseline demographic, clinical, and cognitive characteristics of the Alzheimer's Prevention Initiative (API) Autosomal-Dominant Alzheimer's Disease Colombia Trial

ABSTRACT: Introduction: The API AutosomalDominant AD (ADAD) Colombia Trial is a placebo-controlled clinical trial of crenezumab in 252 cognitively unimpaired 30 to 60-year-old Presenilin 1 (PSEN1) E280A kindred members, including mutation carriers randomized to active treatment or placebo and non-ca...

Full description

Autores:

Tobón Quintero, Carlos Andrés
Lopera Restrepo, Francisco Javier
Ríos Romenets, Silvia
Sink, Kaycee M.
Hu, Nan
Lian, Qinshu
Guthrie, Heather
Smith, Jillian
Cho, William
Mackey, Howard
Langbaum, Jessica B.
Thomas, Ronald G.
Giraldo Chica, Margarita María
Acosta Baena, Natalia
Muñoz Zapata, Claudia Cecilia
Ospina Lopera, Paula Andrea
Tirado Pérez, Victoria Claudia
Henao Arboleda, Eliana
Bocanegra García, Orfa Yamile
Chen, Kewei
Su, Yi
Goradia, Dhruman
Thiyyagura, Pradeep
VanGilder, Paul S.
Luo, Ji
Ghisays, Valentina
Lee, Wendy
Malek Ahmadi, Michael H.
Protas, Hillary D.
Chen, Yinghua
Quiroz Gaviria, Yakeel Tatiana
Reiman, Eric M.
Tariot, Pierre N.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43065

Acceso en línea:

https://hdl.handle.net/10495/43065

Palabra clave:

Alzheimer Disease
Enfermedad de Alzheimer
Antibodies, Monoclonal, Humanized
Anticuerpos Monoclonales Humanizados
Cognition
Cognición
Mutation
Mutación
Neuropsychological Tests
Pruebas Neuropsicológicas
Presenilin-1
Presenilina-1
https://id.nlm.nih.gov/mesh/D000544
https://id.nlm.nih.gov/mesh/D061067
https://id.nlm.nih.gov/mesh/D003071
https://id.nlm.nih.gov/mesh/D009154
https://id.nlm.nih.gov/mesh/D009483
https://id.nlm.nih.gov/mesh/D053764

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc/4.0/