The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer´s disease model mice

ABSTRACT: Alzheimer’s disease (AD) is the most common senile dementia in the world. Although important progress has been made in understanding the pathogenesis of AD, current therapeutic approaches provide only modest symptomatic relief. In this study, we evaluated the neuroprotective effect of quer...

Full description

Autores:

Sabogal Guáqueta, Angélica María
Muñoz Manco, Juan Ignacio
Ramírez Pineda, José Robinson
Lamprea Rodríguez, Marisol
Osorio Durango, Edison
Cardona Gómez, Gloria Patricia

Tipo de recurso:

Article of investigation

Fecha de publicación:

2015

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/36475

Acceso en línea:

https://hdl.handle.net/10495/36475

Palabra clave:

Envejecimiento
Aging
Enfermedad de Alzheimer
Alzheimer Disease
Péptidos beta-Amiloides - metabolismo
Amyloid beta-Peptides - metabolism
Antioxidantes - uso terapéutico
Antioxidants - therapeutic use
Brain
Encéfalo
Trastornos del Conocimiento - prevención & control
Cognition Disorders - prevention & control
Esquema de Medicación
Drug Administration Schedule
Gliosis - prevención & control
Ratones Transgénicos
Mice, Transgenic
Trastornos del Humor - prevención & control
Mood Disorders - prevention & control
Proteínas del Tejido Nervioso - metabolismo
Nerve Tissue Proteins - metabolism
Neuroglía - patología
Neuroglia - pathology
Quercetina - uso terapéutico
Quercetin - therapeutic use

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/