SMYD3 promotes cancer invasion by epigenetic upregulation of the metalloproteinase MMP-9

ABSTRACT: Upregulation of the matrix metalloproteinase (MMP)–9 plays a central role in tumor progression and metastasis by stimulating cell migration, tumor invasion, and angiogenesis. To gain insights into MMP-9 expression, we investigated its epigenetic control in a reversible model of cancer that...

Full description

Autores:

Cook Rada, Alicia María
Medjkane, Souhila
Janski, Natacha
Yousfi, Nadhir
Perichon, Martine
Chaussepied, Marie
Chluba, Johanna
Langsley, Gordon
Weitzman, Jonathan B.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2012

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39553

Acceso en línea:

https://hdl.handle.net/10495/39553

Palabra clave:

Regulación Neoplásica de la Expresión Génica
Gene Expression Regulation, Neoplastic
N-Metiltransferasa de Histona-Lisina
Histone-Lysine N-Methyltransferase
Interacciones Huésped-Parásitos
Host-Parasite Interactions
Metaloproteinasa 9 de la Matriz
Matrix Metalloproteinase 9
Invasividad Neoplásica
Neoplasm Invasiveness
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
Reverse Transcriptase Polymerase Chain Reaction
Western Blotting
Blotting, Western
Bovinos
Cattle
Línea Celular Tumoral
Cell Line, Tumor
Trasplante de Neoplasias
Neoplasm Transplantation
https://id.nlm.nih.gov/mesh/D015972
https://id.nlm.nih.gov/mesh/D011495
https://id.nlm.nih.gov/mesh/D006790
https://id.nlm.nih.gov/mesh/D020780
https://id.nlm.nih.gov/mesh/D009361
https://id.nlm.nih.gov/mesh/D020133
https://id.nlm.nih.gov/mesh/D015153
https://id.nlm.nih.gov/mesh/D002417
https://id.nlm.nih.gov/mesh/D045744
https://id.nlm.nih.gov/mesh/D009368

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/