Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

ABSTRACT: Background: Lithium is a first-line treatment in bipolar disorder, but individual response is variable. Previous studies have suggested that lithium response is a heritable trait. However, no genetic markers of treatment response have been reproducibly identified. Methods: Here, we report...

Full description

Autores:

López Jaramillo, Carlos Alberto
Hou, Liping
Heilbronner, Urs
Degenhardt, Franziska
Adli, Mazda
Akiyama, Kazufumi
Akula, Nirmala
Ardau, Raffaella
Arias, Bárbara
Backlund, Lena
Banzato, Claudio E M

Tipo de recurso:

Article of investigation

Fecha de publicación:

2016

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/45431

Acceso en línea:

https://hdl.handle.net/10495/45431

Palabra clave:

Bipolar Disorder
Trastorno Bipolar
Genetic Variation
Variación Genética
Genome-Wide Association Study
Estudio de Asociación del Genoma Completo
Genotype
Genotipo
Glial Cell Line-Derived Neurotrophic Factor Receptors
Receptores del Factor Neurotrófico Derivado de la Línea Celular Glial
Lithium Compounds
Compuestos de Litio
Phenotype
Fenotipo
Polymorphism, Single Nucleotide
Polimorfismo de Nucleótido Simple
Prospective Studies
Estudios Prospectivos
Treatment Outcome
Resultado del Tratamiento
https://id.nlm.nih.gov/mesh/D001714
https://id.nlm.nih.gov/mesh/D014644
https://id.nlm.nih.gov/mesh/D055106
https://id.nlm.nih.gov/mesh/D005838
https://id.nlm.nih.gov/mesh/D051097
https://id.nlm.nih.gov/mesh/D018020
https://id.nlm.nih.gov/mesh/D010641
https://id.nlm.nih.gov/mesh/D020641
https://id.nlm.nih.gov/mesh/D011446
https://id.nlm.nih.gov/mesh/D016896

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/