A multigenerational pedigree of late-onset Alzheimer’s disease implies new genetic causes

ABSTRACT: We describe the clinical phenotype and pathology of a new autosomal dominant late-onset familial form of Alzheimer’s disease in four extensive kindred originated in a genetically isolated population. Twelve affected and 16 unaffected members of these kindred were examined clinically, and a...

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Autores:

Arcos Burgos, Oscar Mauricio
Palacios Baena, Luis Guillermo
Jiménez Escrig, Adriano
Gómez Tortosa, Estrella
Barón, Manuel
Rabano, Alberto
Yusta, Antonio
Anta, Pilar
Pérez, Immaculada
Hierro, Margarita
Muñoz, David G.
Barquero, Sagrario

Tipo de recurso:

Article of investigation

Fecha de publicación:

2005

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/30999

Acceso en línea:

https://hdl.handle.net/10495/30999

Palabra clave:

Enfermedad de Alzheimer
Alzheimer Disease
https://id.nlm.nih.gov/mesh/D000544
Aislados genéticos
Análisis de segregación complejo

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/