Amaryllidaceae alkaloids in skin cancer management: Photoprotective effect on human keratinocytes and anti-proliferative activity in melanoma cells

ABSTRACT: Skin cancer has high rates of mortality and therapeutic failure. In this study, to develop a multi-agent strategy for skin cancer management, the selective cytotoxicity of several alkaloid fractions and pure alkaloids isolated from Amaryllidaceae species was evaluated in melanoma cells. In...

Full description

Autores:

Castañeda Aedo, Carol Melissa
Bravo Muñoz, Elizabeth
Cortés Rendón, Natalie Charlotte
Bedoya Bedoya, Janeth Eliana
Osorio Durango, Edison
Bastida Armengol, JaumeKarent
Borges, Warley De Souze

Tipo de recurso:

Article of investigation

Fecha de publicación:

2023

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/42241

Acceso en línea:

https://hdl.handle.net/10495/42241

Palabra clave:

Alcaloides - farmacología
Alkaloids - pharmacology
Alcaloides de Amaryllidaceae - farmacología
Amaryllidaceae Alkaloids - pharmacology
Interleucina-6
Interleukin-6
Queratinocitos
Keratinocytes
Melanoma - tratamiento farmacológico
Melanoma - drug therapy
Especies Reactivas de Oxígeno - farmacología
Reactive Oxygen Species - pharmacology
Neoplasias Cutáneas - tratamiento farmacológico
Skin Neoplasms - drug therapy
https://id.nlm.nih.gov/mesh/D000470
https://id.nlm.nih.gov/mesh/D047151
https://id.nlm.nih.gov/mesh/D015850
https://id.nlm.nih.gov/mesh/D015603
https://id.nlm.nih.gov/mesh/D008545
https://id.nlm.nih.gov/mesh/D017382
https://id.nlm.nih.gov/mesh/D012878

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/