Protective effects of caffeine against palmitate-induced lipid toxicity in primary rat hepatocytes is associated with modulation of adenosine receptor A1 signaling

ABSTRACT: Background: Epidemiological evidence has shown an association between coffee consumption and reduced risk for chronic liver diseases, including metabolic-dysfunction-associated liver disease (MALFD). Lipotoxicity is a key cause of hepatocyte injury during MAFLD. The coffee component caffei...

Full description

Autores:

Arroyave Ospina, Johanna Carolina
Buist Homan, Manon
Schmidt, Martina
Moshage, Han

Tipo de recurso:

Article of investigation

Fecha de publicación:

2023

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39596

Acceso en línea:

https://hdl.handle.net/10495/39596

Palabra clave:

Cafeína
Caffeine
Farmacología
Pharmacology
Hepatocitos
Hepatocytes
Palmitatos
Palmitates
Receptor de Adenosina A1
Receptor, Adenosine A1
Metabolismo
Metabolism
https://id.nlm.nih.gov/mesh/D002110
https://id.nlm.nih.gov/mesh/D010600
https://id.nlm.nih.gov/mesh/D022781
https://id.nlm.nih.gov/mesh/D010168
https://id.nlm.nih.gov/mesh/D043682
https://id.nlm.nih.gov/mesh/D008660

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/