Determination of therapeutic equivalence of generic products of gentamicin in the neutropenic mouse thigh infection model

ABSTRACT: Background: Drug regulatory agencies (DRA) support prescription of generic products of intravenous antibiotics assuming therapeutic equivalence from pharmaceutical equivalence. Recent reports of deaths associated with generic heparin and metoprolol have raised concerns about the efficacy a...

Full description

Autores:

Zuluaga Salazar, Andrés Felipe
Agudelo Pérez, María
Rodríguez Jaramillo, Carlos Andrés
Vesga Meneses, Omar
Cárdeno Sánchez, John Jairo

Tipo de recurso:

Article of investigation

Fecha de publicación:

2010

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/39095

Acceso en línea:

https://hdl.handle.net/10495/39095

Palabra clave:

Antiinfecciosos
Anti-Infective Agents
Infecciones Bacterianas - Complicaciones
Bacterial Infections - complications
Modelos Animales de Enfermedad
Disease Models, Animal
Medicamentos Genéricos
Drugs, Generic
Gentamicinas
Gentamicins
Pruebas de Sensibilidad Microbiana
Microbial Sensitivity Tests
Neutropenia
Organ Specificity
Equivalencia Terapéutica
Therapeutic Equivalency
Muslo
Thigh
Especificidad de Órganos
https://id.nlm.nih.gov/mesh/D000890
https://id.nlm.nih.gov/mesh/D001424
https://id.nlm.nih.gov/mesh/D004195
https://id.nlm.nih.gov/mesh/D016568
https://id.nlm.nih.gov/mesh/D005839
https://id.nlm.nih.gov/mesh/D008826
https://id.nlm.nih.gov/mesh/D009503
https://id.nlm.nih.gov/mesh/D009928
https://id.nlm.nih.gov/mesh/D013810
https://id.nlm.nih.gov/mesh/D013848

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/