Variants in the IFNγ transcription factor genes TBET, STAT1, STAT4, and HLX and the risk of pulmonary tuberculosis in a Colombian population: a case-control study

ABSTRACT: Introduction: Interferon gamma (IFNγ) is the most potent cytokine involved in the control of Mycobacterium tuberculosis (Mtb), the etiological agent of human tuberculosis (TB). Patients with active TB present reduced levels of IFNγ, which may explain the lack of effective immunity against...

Full description

Autores:

Sánchez Pino, María Dulfary
García Moreno, Luis Fernando
Barrera Robledo, Luis Fernando
Lefebvre, Céline

Tipo de recurso:

Article of investigation

Fecha de publicación:

2013

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/43133

Acceso en línea:

https://hdl.handle.net/10495/43133
https://revistabiomedica.org/index.php/biomedica/article/view/790

Palabra clave:

Regulación de la Expresión Génica
Gene Expression Regulation
Predisposición Genética a la Enfermedad
Genetic Predisposition to Disease
Proteínas de Homeodominio - genética
Homeodomain Proteins - genetics
Interferón gamma - genética
Interferon-gamma - genetics
Polimorfismo de Nucleótido Simple
Polymorphism, Single Nucleotide
Factor de Transcripción STAT1 - genética
STAT1 Transcription Factor - genetics
Factor de Transcripción STAT4 - genética
STAT4 Transcription Factor - genetics
Proteínas de Dominio T Box - genética
T-Box Domain Proteins - genetics
Factores de Transcripción - genética
Transcription Factors - genetics
Tuberculosis Pulmonar - genética
Tuberculosis, Pulmonary - genetics
Mycobacterium tuberculosis
Estudios de Casos y Controles
Case-Control Studies
https://id.nlm.nih.gov/mesh/D005786
https://id.nlm.nih.gov/mesh/D020022
https://id.nlm.nih.gov/mesh/D018398
https://id.nlm.nih.gov/mesh/D007371
https://id.nlm.nih.gov/mesh/D020641
https://id.nlm.nih.gov/mesh/D050794
https://id.nlm.nih.gov/mesh/D050797
https://id.nlm.nih.gov/mesh/D020825
https://id.nlm.nih.gov/mesh/D014157
https://id.nlm.nih.gov/mesh/D014397
https://id.nlm.nih.gov/mesh/D009169
https://id.nlm.nih.gov/mesh/D016022

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/