Immunotherapy in Melanoma: Role of TIGIT and LAG-3 on the antitumor immune microenvironment

Melanoma, is a malignant tumor arising from melanocytes. Given the ability of melanoma cells to inactivate lymphocytes, immunotherapy in melanoma has focused on using immune checkpoint inhibitors (ICIs) to counteract immune evasion. The lymphocyte activation gene 3 (LAG-3) and the inhibitory recepto...

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Autores:
Tipo de recurso:
Fecha de publicación:
2023
Institución:
Universidad Pedagógica y Tecnológica de Colombia
Repositorio:
RiUPTC: Repositorio Institucional UPTC
Idioma:
spa
OAI Identifier:
oai:repositorio.uptc.edu.co:001/15368
Acceso en línea:
https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/15041
https://repositorio.uptc.edu.co/handle/001/15368
Palabra clave:
Anticuerpos monoclonales
Terapia antitumoral combinada
punto de control inmunitario
LAG-3
TIGIT
células T
Monoclonal antibodies
T cells
LAG-3
immune checkpoint
combined antitumor therapy
TIGIT
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http://purl.org/coar/access_right/c_abf2