Potential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantation.

Upregulation of tissue factor (TF) expression on activated donor endothelial cells (ECs) triggered by the immune response (IR) has been considered the main initiator of consumptive coagulopathy (CC). In this study, we aimed to identify potential factors in the development of thrombocytopenia and CC...

Full description

Autores:

Cooper, David KC C.
Bogdanov, Vladimir Y.
Hara, Hidetaka
Long, Cassandra
Lin, Chihche
Stolz, Donna Beer
Enjyoji, Keiichi Ichi
Robson, Simon Christopher
Ayares, David L.
Dorling, Anthony
Ezzelarab, Mohamed B.
Echeverri Junca, Gabriel Jaime
Ekser, Burcin
Gridelli, Bruno G.

Tipo de recurso:

Article of investigation

Fecha de publicación:

2012

Institución:

Universidad ICESI

Repositorio:

Repositorio ICESI

Idioma:

eng

OAI Identifier:

oai:repository.icesi.edu.co:10906/78505

Acceso en línea:

http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=31&SID=4BDShD6T2KTBoAZU7Ey&page=1&doc=1
http://hdl.handle.net/10906/78505
http://dx.doi.org/10.1111/j.1432-2277.2012.01506.x

Palabra clave:

Trombocitopenia
Coagulopatias
Xenotrasplantes
Trasplante de higado
Ciencias socio biomédicas
Medical sciences

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/4.0/